Having had a rather large experience in the treatment of these cases, and feeling that the profession, as a rule, have not very definite ideas on the subject, I am induced to place before my readers, in a very brief and practical manner, a line of treatment which has proved of service in my own practice. In the first place, I shall assume that the question of the patient being pregnant is set a...

Dear Editor, We fully agree with Sotiriadis and Makrydimas that only a large, randomized placebo-controlled trial could provide reliable information on the value of progestogens treatment in threatened abortion. However, the main aim of our study was to compare serum hormonal profiles and urine progesterone-induced blocking factor (PIBF) concentrations between women with threatened abortion and...

human leukocyte antigen-g which is an immune tolerance effecter molecule has an important role in the maintenance of fetus during pregnancy. abortion is one of the complications of pregnancy period.  in this research, we have studied levels of hla-g 5, hla-g7 isoforms in the abortion-threatened pregnant women in comparison with controls. in a case-control study, 101 abortion-threatened women an...

Plasma diamine oxidase levels were assayed in 66 patients who presented with pregnancy complicated by threatened abortion. Levels within the normal range were associated with continuing pregnancies, whereas levels below the normal range were associated with subsequent abortion. Among those patients in whom gestation was greater than eight weeks, 66.6% of diamine oxidase levels correctly predict...

The immunotolerant human leukocyte antigen-G (HLA-G) molecules have a major role in fetal-maternal tolerance during pregnancy. Interaction between these molecules and uterine natural killer (uNK) cells inhibitory receptors prevents NK cell invasion against fetus trophoblast cells. The aim of this study was to evaluate the percentages of uNK cells and HLA-G1 and HLA-G5 isoforms expression in vag...

BACKGROUND Threatened abortion is the most common complication in the first half of pregnancy. Most of these pregnancies continue to term with or without treatment. Spontaneous abortion occurs in less than 30% of these women. Threatened abortion had been shown to be associated with increased incidence of antepartum haemorrhage, preterm labour and intra uterine growth retardation. OBJECTIVE Th...

Threatened miscarriage is a common complication of pregnancy. Despite initial viability confirmation by ultrasound scan, some of these patients had further spontaneous abortion. A highly sensitive and specific biomarker would be useful to determine the outcome of pregnancy and to prevent emotional impact to these women. A prospective 14-month cohort study was conducted in the Obstetrics and Gyn...